By BEN HARRISSydney Rebels got win number 34 but only just.The three-time defending mixed open champions were pushed to the edge by ACT Pirates on day two of the 2014 X-Blades National Touch League at Coffs Harbour.After racking up consecutive win number 33 by downing North Queensland Tropical Cyclones 9-4, the Rebels had to dig deep to defeat the Pirates 12-11 in round four.Rebels lead Pool A by four points and will meet second-placed Sydney Mets on day three.The Pirates and Cyclones are third and fourth followed by Hunter Western Hornets and Japan.In Pool B, Brisbane City Cobras are five from five and lead the group.South Queensland Sharks were circling the Cobras as the two teams were undefeated, however last year’s runners-up hammered their southern neighbours 12-3 to go it alone on top.Behind the Sharks are Sunshine Coast Pineapples in third and Northern Eagles in fourth. They are followed by Northern Territory, Defence Warriors and Sydney Scorpions.Five Queensland sides dominate the men’s T-League division.South Queensland Sharks (A) lead Pool A and Brisbane City Cobras are in front in Pool B.But closing the gap are Central Queensland Bulls and Sunshine Coast Pineapples – both in Pool A – and South West Queensland Swans in Pool B.Rebels and Scorpions are the only NSW sides putting up a fight to the Queenslanders while the international teams, Japan and Papua New Guinea, continued to impress.It’s tight in Pool A of the women’s T-League division with Hornets, Swans, Cobras, Victoria and Northern Territory all within eight points of each other.It is a little spread out in Pool B with Scorpions and South Australia leading the way.The Sharks remain unbeaten following six matches of the men’s 30s division.They are in front of Pineapples, Hornets and Scorpions.Scorpions have their own problems as ACT and Sydney Mets are on the same points as Scorpions but behind on percentages.Swans finished on top in the women’s 35s and will play the winner of the Hornets-Pirates preliminary final match.Cyclones and Northern Territory play in the other preliminary final with the loser eliminated from the title race.Scorpions and Sharks are equal on points in the men’s 40s but the Sydney side has a game up their sleeve.Defence Warriors are third, and Hornets and Cyclones are in a battle for fourth spot.Scorpions will be hard to beat in the women’s 40s after winning all their round matches.They will meet Hornets or Northern Eagles in a qualifying final tomorrow. Western Tigers take on ACT in the other qualifying final.Men’s 45s seems to be a two-horse race with Scorpions and Hornets undefeated.The men’s 50s is set to go down to the wire with four points separating the top four.Mets, Pineapples, Sharks and Hornets occupy the top four positions in the division.Eagles, Cyclones and Scorpions will be battling each other for the two spots in the men’s 55s.In the senior mixed, Sharks have all but confirmed their spot in the grand final but the Hornets and Cobras are going head-to-head for the last spot.You can keep up-to-date with all of the latest news and information from the 2014 X-Blades National Touch League in the following ways:Websiteswww.ntl.mytouchfooty.comwww.austouch.com.auSocial MediaFacebook – www.facebook.com/touchfootballaustraliaTwitter – www.twitter.com/touchfootyaus (be sure to use the hashtag #NTL2014)Instagram – www.instagram.com/touchfootballaustraliaYouTube – www.youtube.com/touchfootballausRelated LinksNTL results day two
TagsTransfersAbout the authorPaul VegasShare the loveHave your say Chelsea striker Giroud: I do not accept this situationby Paul Vegas13 days agoSend to a friendShare the loveOlivier Giroud admits he’s unhappy with his situation at Chelsea.The France international, who scored the only goal in Friday’s win over Iceland, has hinted at talks with Frank Lampard but insisted he would never seek to insult his manager.”Accept it? No, I do not accept it,” he told Le Pelerin.”You do not have to be fatalistic in certain situations. I have always been respectful and humble. Even if I do not agree with the coach, I do not criticise him.”But in myself, I cannot accept it because I know what I’m worth on a pitch. Last year, when I felt that I deserved to play, I asked the coach for explanations.”
Michigan may have completely overhauled its coaching staff this offseason, but clearly, Michigan State and its fans aren’t conceding state bragging rights any time soon. Thursday night, one MSU board of trustees member made that clear.Mitch Lyons, the Vice-Chair of the Michigan State Board of Trustees, had a little fun with new Michigan tight ends coach Jay Harbaugh on Twitter. Harbaugh, clearing trying to endear himself to his new fan base, asked his followers if it was legal to own a Wolverine as a pet. Lyons responded, telling Harbaugh he should ask Coach Mark Dantonio. If you aren’t connecting the dots, he’s claiming that Dantonio owns the Wolverines.@JayHarbaugh @ryanschuiling Ask Coach D…..#GoGreen— Mitch Lyons (@mlyons85) January 23, 2015Considering Dantonio is 6-2 against Michigan in his time in East Lansing, this is an A+ troll job. Unfortunately, Harbaugh never responded, instead choosing to ignore the comment.
Source:https://www.ninds.nih.gov/News-Events/News-and-Press-Releases/Press-Releases/Every-cell-has-story-tell-brain-injury Reviewed by James Ives, M.Psych. (Editor)Oct 5 2018Traumatic head injury can have widespread effects in the brain, but now scientists can look in real time at how head injury affects thousands of individual cells and genes simultaneously in mice. This approach could lead to precise treatments for traumatic brain injury (TBI). The study, reported in Nature Communications, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.”Instead of clustering responses according to categories of cells in TBI, we can now see how individual cells in those groups react to head injury,” said Patrick Bellgowan, Ph.D., program director at NINDS.University of California, Los Angeles professors Fernando Gomez-Pinilla, Ph.D. and Xia Yang, Ph.D., along with their colleagues, used a novel method known as Drop-seq to closely look at individual brain cells in the hippocampus, a region involved in learning and memory, after TBI or in uninjured control animals. Drop-seq allows thousands of cells and genes to be analyzed simultaneously. Its creation was in part funded by the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative.”These tools provide us with unprecedented precision to pinpoint exactly which cells and genes to target with new therapies,” said Dr. Yang. “Another important aspect to this study was the highly collaborative and multidisciplinary nature of the work. Lots of people, from many different scientific areas, made this study possible.”In one set of experiments the team looked at TBI’s effects on gene expression activity in individual cells. They found that certain genes were upregulated or downregulated across many different cell types, suggesting these genes may play important roles in TBI. Some of these genes are also known to be involved in diseases, such as Alzheimer’s disease, which may help explain how TBI can be a risk factor for other disorders. For example, Drs. Yang and Gomez-Pinilla’s groups observed altered activity in genes that are involved in regulating the amyloid protein, which builds up in Alzheimer’s.Related StoriesMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsResearch team to create new technology for tackling concussionAn active brain and body associated with reduced risk of dementiaIn particular, the genomic analysis revealed that the activity of the Ttr gene, which is involved in both thyroid hormone transport and scavenging of amyloid protein in the brain, was increased in many cells following TBI, suggesting the thyroid hormone pathway may be a potential target for therapy. Drs. Gomez-Pinilla and Yang’s teams treated animals with the thyroid hormone thyroxine (T4) 1 and 6 hours after brain injury and saw that they performed much better on learning and memory tasks compared to animals that received a placebo.The team identified 15 clusters of cells based on gene activity, including two clusters, named Unknown1 and Unknown2, the cells of which had not been described previously in the hippocampus. Further analysis of these clusters revealed that the cells in the Unknown1 group were involved in cell growth and migration and the cells in Unknown2 were involved in cell differentiation during development. The findings in this study also reveal that although two cells may have similar structure and shape, their functions, as suggested by the analysis of gene activity, may differ.”We now know the secret life of single cells, including how they coordinate with other cells and how vulnerable they are to injury,” said Dr. Gomez-Pinilla. “In addition, seeing which types of genes, including genes involved in metabolism, were involved across many cell types helps identify processes that may be critical in TBI.”Future studies will examine how TBI affects cells in areas other than the hippocampus. In addition, more research is needed to learn about long-term effects of TBI. Analyzing individual cells and genes may identify potential therapies for TBI.
It’s a much safer drug than CBD, with no abuse potential and doesn’t require the cultivation of hemp.”Mark Mascal, professor in the UC Davis Department of Chemistry. Mascal’s laboratory at UC Davis carried out the work in collaboration with researchers at the University of Reading, U.K.Related StoriesNanotechnology-based compound used to deliver hepatitis B vaccineOlympus Europe and Cytosurge join hands to accelerate drug development, single cell researchTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTProducts containing CBD have recently become popular for their supposed health effects and because the compound does not cause a high. CBD is also being investigated as a pharmaceutical compound for conditions including anxiety, epilepsy, glaucoma and arthritis. But because it comes from extracts of cannabis or hemp plants, CBD poses legal problems in some states and under federal law. It is also possible to chemically convert CBD to tetrahydrocannabinol (THC), the intoxicating compound in marijuana.8,9-Dihydrocannabidiol (H2CBD) is a synthetic molecule with a similar structure to CBD. Mascal’s laboratory developed a simple method to inexpensively synthesize H2CBD from commercially available chemicals. “Unlike CBD, there is no way to convert H2CBD to intoxicating THC,” he said.One important medical use of cannabis and CBD is in treatment of epilepsy. The U.S. Food and Drug Administration has approved an extract of herbal CBD for treating some seizure conditions and there is also strong evidence from animal studies.The researchers tested synthetic H2CBD against herbal CBD in rats with induced seizures. H2CBD and CBD were found to be equally effective for the reduction of both the frequency and severity of seizures.Mascal is working with colleagues at the UC Davis School of Medicine to carry out more studies in animals with a goal of moving into clinical trials soon. UC Davis has applied for a provisional patent on antiseizure use of H2CBD and its analogues, and Mascal has founded a company, Syncanica, to continue development.Source:University of California – DavisJournal reference:Mascal, M. et al. (2019) Synthetic, non-intoxicating 8,9-dihydrocannabidiol for the mitigation of seizures. Scientific Reports. doi.org/10.1038/s41598-019-44056-y. Reviewed by Kate Anderton, B.Sc. (Editor)May 28 2019A synthetic, non-intoxicating analogue of cannabidiol (CBD) is effective in treating seizures in rats, according to research by chemists at the University of California, Davis.The synthetic CBD alternative is easier to purify than a plant extract, eliminates the need to use agricultural land for hemp cultivation, and could avoid legal complications with cannabis-related products. The work was recently published in the journal Scientific Reports.
SHARE SHARE EMAIL real estate COMMENTS Digital transformation company, UST Global, has inaugurated new office space at Kochi’s World Trade Centre building, two floors of which will serve as an offshore delivery centre (ODC) for global clients.Clients and the company’s leadership team including Sunil Balakrishnan, Global Head, Development Centre Operations, and Vivek Sarin, General Manager, were present on the occasion. PAN-INDIA PRESENCEThe 1,000+ seater space in the ninth and tenth floors of the Brigade World Trade Centre at Infopark, Kochi, will host ODCs for clients primarily in the BFSI (banking, financial services, and insurance) and retail sectors. The World Trade Centre Kochi is itself located in the heart of the booming IT hub of Kakkanad, with state-of-the-art infrastructure, grade A Specifications and LEED Gold pre-certification.UST Global currently has over 2,000 associates at the Kochi centre and over 15,000 associates in India. Last year, the company opened a new delivery centre in Hyderabad as part of its global expansion plans.Alexander Varghese, Chief Administrative Officer & Country Head, UST Global, said Kerala is a key geography for them in terms of expansion and availability of talent. TO HIRE ASSOCIATESAccording to Sunil Balakrishnan, Kochi is well positioned in terms of its modern infrastructure and talent to meet the needs of the company’s global clients. “We are excited, and look forward to hiring associates who are aligned to our vision of ‘Transforming Lives’ using new-age digital technologies,” he added.With regional headquarters in California, Singapore, and London, and over 35 offices across the world, UST Global uses partners with multinational clients, which includes over 50 Fortune 500 clients. The company’s current global footprint spans the the US, India, Mexico, Spain, Denmark, the UK, Germany, Poland, Singapore, the Philippines, Malaysia, Taiwan, China, and Australia. It also has large dedicated information technology delivery centres in India, the US, Mexico, Spain, and the Philippines. SHARE April 17, 2019 COMMENT UST Global Published on
India Today Web Desk New DelhiJuly 12, 2019UPDATED: July 12, 2019 20:33 IST Goa Chief Minister Pramod Sawant said that he has asked three GFP ministers and Rohan Khaunte to resign from the cabinet. (Photo: ANI)A day after 10 MLAs switched from the Congress to the Bharatiya Janata Party (BJP), Goa Chief Minister Pramod Sawant asked three Goa Forward Party (GFP) ministers and one Independent MLA to resign from his ministry. The lawmakers were asked to step down as new faces would be inducted in the state cabinet on Saturday.The three GFP ministers who have been asked to resign are Vijai Sardesai, Vinod Palyekar, and Jayesh Salgaonkar and the Independent MLA is Rohan Khaunte.Pramod Sawant along with the 10 MLAs on Friday met Home Minister Amit Shah and working president JP Nadda in Delhi.Pramod Sawant said, “I have asked three GFP ministers and Khaunte to resign from the cabinet. I have given them the instructions as per the orders from my high command.” The Goa chief minister also said that he will be four new ministers on Saturday. He, however, did not reveal the names of the new ministers.A senior state BJP leader had said earlier in the day that Sawant would induct BJP MLA and Deputy Speaker of Goa Assembly Michael Lobo, and three of the ten MLAs who have switched over from the Congress.Reacting to the recent developments in Goa, the GFP said it would take a decision only after speaking to the central leadership of the BJP.GFP, in a statement, said that the party is a part of the National Democratic Alliance (NDA) and had joined the state government after having talks with the national leadership of the Bharatiya Janata Party (BJP). It also said that the present BJP leaders in Goa were not part of the discussions.”We are a part of the NDA and had joined the BJP-led state government after talks with the national leadership of the BJP. The present state BJP leaders were not part of the discussions then,” the GFP said.The Goa Forward Party also said that it has not received any official communication from the central leaders of the BJP. On the contrary, the party said, it has received indications that the matter will be sorted out soon.”As such we will take appropriate steps only after talking with NDA leadership at the Centre. We haven’t yet received any official communication from BJP central leaders. On the contrary, we have received indications that the matter will be sorted out amicably,” the party said.Also Read | Congress MLA likens Goa crisis to political prostitutionAlso Read | 3 ex-Congress MLAs likely to be inducted in Goa cabinetAlso Watch | Leaderless Congress headed towards self-destruction?For the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byChanchal Chauhan Next Goa CM Pramod Sawant seeks resignation of 3 ministers, independent MLA to induct new facesThe three GFP ministers who have been asked to resign are Vijai Sardesai, Vinod Palyekar, and Jayesh Salgaonkar and the Independent MLA is Rohan Khaunte.advertisement